Anaesthesia and intensive care

• Near infrared spectroscopy (NIRS) for monitoring of paediatric patients at risk of low perfusion following cardiac surgery

 

Cancer/Oncology and radiotherapy

• Ablative techniques for the treatment of localised prostate cancer *update
• STAR^TM Tumor Ablation System *update
• Selective internal radiation therapy for the treatment of liver cancer
• Reginonal hyperthermia for soft-tissue sarcoma
• Gene expression profiling of breast cancer *update
• Magnetic Resonance (MR)-guided, high-intensity focussed ultrasound for cancer of the brain, liver, bone, breast and prostate
• Theralite^TM for treatment of renal failure in patients with multiple myeloma
• MelaFind® for the detection of melanoma among atypical skin lesions
• Inert liquid-to-solid gels for prostate-rectum separation during prostate radiation therapy *update
• Margin Probe® to assess surgical margins during lumpectomy for breast cancer
• An assay to identify biopsy-negative prostate cancer
• Automated Breast Ultrasound
• BreastNext®: a 14-gene sequencing panel for the diagnosis of hereditary breast/ovarian cancer
• Multi-catheter interstitial brachytherapy for early stage breast cancer *Update
• Microwave ablation for hepatic tumours *Update
• MR-guided focused ultrasound for cancer of the brain, liver, bone, breast and prostate *Update
• A compendium of technologies for the diagnosis, screening or treatment of prostate cancer *March 2015
• Prostatic artery embolisation to treat benign prostatic hyperplasia
• Ablative Techniques for the Treatment of Localised Prostate Cancer
• Theralite^TM for renal failure in patients with multiple myeloma *Update
• Molecular testing for prostate cancer prognosis Oncology and radiotherapy
• MRI screening/diagnosis and monitoring for prostate cancer
• Pressurised intraperitoneal aerosol chemotherapy
• Circulating tumour DNA assays
• Magnetic resonance thermometry-guided laser interstitial thermal therapy for intracranial neoplasms *Update
• STAR^TM Tumor Ablation System
• BioZorb^TM Surgical Site Delineator
• SureFire® Precision Chemoembolization Infusion System
• Gallium-68 Prostate Specific Membrane Antigen (PSMA)
• SentiMag® and Sienna+® system for sentinel lymph node biopsy in breast cancer *Update
• Blood and stool biomarker testing for colorectal cancer screening *Update

 

Cardiovascular disease & vascular surgery

• Transcatheter mitral valve replacement for several mitral regurgitation - Dec 2015
• Transcatheter aortic valve implantation (TAVI) - The current state of play - Dec 2014
• Screening for coronary artery disease using CT calcium scoring
• Endovascular clot retrieval with thrombolysis for ischaemicstroke
• Transcatheter mitral valve replacement for severe mitral regurgitation
• Ultra-filtration for patients with decompensated heart failure *Update
• Zio patch for diagnosis of cardiac arrhythmias
• Drug-eluting stents and balloons for the treatment of peripheral vascular disease
• High sensitivity troponin assays for the diagnosis of myocardial infarction *Update
• Total artificial heart for end-stage refractory biventricular heart failure
• Percutaneous venoplasty for the treatment of chronic cerebrospinal venous insufficiency (CCSVI) in multiple sclerosis
• Implantable carotid sinus baroreflex device for treatment of drug resistant hypertension *Update
• Percutaneous Pulmonary Valve Implantation *Update
• Carillon Mitral Contour System for Mitral Regurgitation *Update
• Extracorporeal shock wave therapy for the treatment of angina *Update
• MediGuide for intravascular evaluation of coronary anatomy
• Near infrared spectroscopy (NIRS) for monitoring of paediatric patients at risk of low perfusion following cardiac surgery
• LeGoo®: reverse thermosensitive polymer gel for the temporary occlusion of blood vessels during surgery
• The Sapien^TM and Sapien XT^TM transcatheter aortic valve implantation (TAVI) devices for the treatment of symptomatic aortic valve stenosis
• Microbial sealant to reduce surgical site infections following coronary artery bypass graft
• Health Buddy® for telehealth patients
• LifeStent® vascular stent for symptomatic lesions of the superficial fermoral or proximal popliteal artery
• Sutureless aortic valve replacement in patients with severe aortic valve stenosis
• The use of BNP to monitor and guide treatment of heart failure patients
• External aortic root support in Marfan syndrome
• Biodegradable stents
• Cardiovascular Magnetic Resonance (CMR) for diagnosis of coronary heart disease
• Aquadex FlexFlow^TM: Ultra-filtration for patients with decompensated heart failure
• Mechanical chest compression devices for patients experiencing cardiac arrest *Update
• MGuard^TM: novel mesh covered bare metal stent
• Sternum support vests to prevent sternal dehiscence
• AIGISRX® Antibacterial Envelope for preventing infection in implanted cardiac devices
• Inferior vena cava filters in the management of patients considered to be at high-risk of acute venous thromboembolism
• Drug eluting stents with CD34 antibodies for the treatment of coronary artery disease
• Implantable carotid sinus baroreflex device for the treatment of drug-resistant hypertension *Update
• Catheter ablation for atrial fibrillation [Partial disinvestment]
• Atrial fibrillation screening
• Intensive upper limb stroke rehabilitation
• Renal denervation *Update
• Sutureless aortic valve replacement in patients with severe aortic valve stenosis *Update
• ROX Coupler for Treatment-resistant Hypertension
• Leadless Pacemaker
• Bioresorbable vascular scaffolds for coronary artery disease

 

Ear, nose and throat (ENT)

• Balloon Sinuplasty for Chronic Rhinosinusitis *Update
• Basic fibroblast growth factor (b-FGF) for the treatment of tympanic membrane perforation
• Bilateral bone-anchored hearing aid (BAHA®) implantation for bilateral hearing loss
• Basic fibroblast growth factor (b-FGF) for the treatment of tympanic membrane perforation *Update
• Radiofrequency Ablation for Hypertrophy of the Inferior Nasal Turbinates
• LINX® reflux management system *Update

 

Endocrine, nutritional and metabolic

• Closed-loop Insulin Delivery System for the management of hypoglycaemia *Update
• Intravitreal corticosteroid implant for the treatment of diabetic macular oedema
• EndoBarrier® gastrointestinal liner for obesity *Update
• Vagus nerve blocking and gastric artery embolisation for obesity *Extended

 

Gastrointestinal, pancreatic and liver disease

• Faecal microbiota transplantation *Update
• Exalenz BreathID® breath test device for the diagnosis of liver disease
• EndoBarrier® gastrointestinal liner for obesity *Update
• SpyGlass® direct visualization system *Update
• Endoscopic pancreatic stenting for prophylaxis of pancreatic fistula after distal pancreatectomy
• LINX® Reflux Management System for the treatment of gastro-oesophageal reflux
• Enhanced liver fibrosis test *Update
• Stem cell transplantation for biologic-resistant Crohn’s disease
• Vagus nerve blocking and gastric artery embolisation for obesity *Extended
• Microwave ablation for hepatic tumours *Update
• Ovation® iX Abdominal Stent Graft System
• Computed tomography to rule out suspected appendicitis in adults and reduce the negative appendectomy rate
• Blood and stool biomarket testing for colorectal cancer screening *Update
• LINX® reflux management system *Update

 

General Medicine

• Medication Compliance Technologies
• Replacement of peripheral venous catheters by clinical indications
• Online programs for weight loss
• New and emerging organ perfusion systems
• Remote presence robots in telemedicine
• PATHFAST Presepsin chemiluminescent enzyme immunoassay for the diagnosis and prognosis of sepsis
• CelluTome^TM Epidermal Harvesting System for the treatment of acute or chronic wounds

 

Genetics

• Gene expression profiling of breast cancer *Update
• Non-invasive prenatal testing (NIPT)
• BreastNext^TM: a 14-gene sequencing panel for the diagnosis of hereditary breast/ovarian cancer
• Antenatal Placental Growth Factor screening for pre-eclampsia toxaemia
• Massively Parallel Sequencing
• Neonatal screening for lysosomal storage disorders *Update
• Circulating tumour DNA assays

 

Haematology and blood products

• An Overview of Emerging Home Renal Dialysis Technologies including Nx stage
• Rotational thromboelastometry (ROTEM®) – targeted therapy for coagulation management in patients with massive bleeding
• Extracorporeal photopheresis for the treatment of graft versus host disease following bone marrow transplantation

 

Infectious diseases

• Rapid tests for Chlamydia trachomatis *Update
• MALDI-TOF MS for detection of antibiotic resistant bacteria

 

Mental health

• Columbia Suicide Severity Rating Scale

 

Neurology and neurosurgery

• Therapeutic hypothermia for intracranial hypertension following traumatic brain injury
• Technologies for the Management of Stroke
• Tumour treating fields for glioblastoma multiforme
• Cerecyte (bioactive) coils for the treatment of intracranial aneurysms *Update
• Biomarkers for the diagnosis and management of traumatic brain injury (TBI)
• Magnetic resonance thermometry-guided laser interstitial thermal therapy for intracranial neoplasms *Update
• MR-guided focused ultrasound for cancer of the brain, liver, bone, breast and prostate *Update
• Brain implant to predict epileptic seizures (Status Report)
• Miethke proSA adjustable gravitational shunt for hydrocephalus

 

Obstetrics and Gynaecology

• Natural orifice transluminal endoscopic surgery (NOTES): cholecystectomy *Update
• Single-incision min-sling system for female stress urinary incontinence
• Antenatal Placental Growth Factor screening for pre-eclampsia toxaemia
• HPV OncoTect^TM E6, E7 mRNA assay to guide colposcopy referral in cervical cancer screening
• Fractional CO2 laser treatment of vulvovaginal atrophy

 

Ophthalmology

• Femtosecond lasers for cataract surgery *update
• Intravitreal corticosteroid implant for the treatment of diabetic macular oedema
• EyeOP1: Ophthalmic high intensity focussed ultrasound for glaucoma
• IRay for wet age-related macular degeneration
• Argus II Retinal prosthesis *update

 

Orthopaedics

• Barricaid prosthesis for partial annulus replacement: update March 2017 *update
• Barricaid prosthesis for partial annulus replacement: March 2015
• InSpace biodegradable subacromial spacer for the treatment of rotator cuff tears

 

Paediatrics and neonatology

• Near infrared spectroscopy (NIRS) for monitoring of paediatric patients at risk of low perfusion following cardiac surgery
• Neonatal screening for lysosomal storage disorders
• Pulse oximetry for detecting heart defects in newborns

 

Radiology, imaging and nuclear medicine

• PET-MRI integrated hybrid scanners
• 90Y Zevalin for the treatment of non-Hodgkins's lymphoma
• MRIdian system for MRI-guided radiotherapy
• Computed tomography to rule out suspected appendicitis in adults and reduce the negative appendectomy rate

 

Rehabilitation and disability

• Autologous blood injection for soft tissue injury
• Platelet-rich plasma for the treatment of knee osteoarthritis
• High-frequency spinal cord stimulation and dorsal root ganglion stimulation for chronic pain

 

Renal disease and urology

• Endovascular arteriovenous fistula creation system
• An Overview of Emerging Home Renal Dialysis Technologies including Nx stage
• Theralite for treatment of renal failure in patients with multiple myeloma
• Theralite for renal failure in patients with multiple myeloma: Update November 2014 *update
• Stenting versus medical therapy for atherosclerotic renal artery stenosis

 

Respiratory disease and thoracic medicine

• Endobronchial valves for patients with advanced heterogeneous emphysema: Update March 2017 *update
• Upper airway stimulation for obstructive sleep apnoea *update
• Endobronchial valves for patients with advanced heterogeneous emphysema: March 2015
• Pleurx catheter system for the treatment of malignant pleural effusion: August 2012
• Hypoglossal nerve stimulation for sleep apnoea
• RePneu Lung Volume Reduction Coils for patients with advanced emphysema 
• The RePneu Coil System and other bronchoscopic lung volume reduction treatments for advanced emphysema *extended
• PleurX catheter system for the treatment of malignant pleural effusion: July 2015 *update
• Non-Invasive Open Ventilation (NIOV) System for Respiratory Insufficiency

 

Surgery

• EndoBarrier gastrointestinal liner for obesity *update
• Robotic-assisted lung resection
• Antibiotics versus appendectomy for uncomplicated appendicitis
• SentiMag and Sienna+ for sentinel lymph node localisation in breast cancer
• LeGoo® : reverse thermosensitive polymer gel for the temporary occlusion of blood vessels during surgery *update
• Microbial sealant to reduce surgical site infections following coronary artery bypass graft *update
• Vagus nerve blocking and gastric artery embolisation for obesity *extended
• Enhanced Recovery after Surgery (ERAS) Program for Hip and Knee Arthroplasty

 

Transplantation

• Stem cell transplantation for biologic-resistant Crohn’s disease